What is Microsatellite Instability?

Written for Our Cancer Stories.

Excerpt


Colorectal cancer, the third most common cancer worldwide, has many causes. While some of these are external and a result of our diet or lifestyle, others originate from within the body itself. In many cases of colorectal cancer, however, it is a combination of risk factors and other causes that lead to the formation of cancerous growth in the colon. As such, it often is difficult to identify the exact cause of the cancer.

Nonetheless, years of research have helped us to identify different characteristics (or biomarkers) that are associated with colorectal cancer. Of the different biomarkers, microsatellite instability or MSI has been identified as a way to determine the type of colorectal cancer a patient is carrying.

In this article, we delve deeper into what MSI is and how it impacts colorectal cancer detection, diagnosis and treatment.


Read the full article here.